Azoline: More from Dr. Nase
Great question Tim. Fungi rarely become resistant to oral
antifungals, but they certainly do come back in moderate to severe
cases. One of the keys to combating seb derm successfully is
knocking the yeast count down to near zero (although normal healthy
skin always has millions of organisms including yeast). The problem
with topicals and first generation oral antifungals is that they
only knock the abnormal count down by 35% to 50%. Now this results
in very good clearance of seb derm, but the patients’ yeast count is
still off the chart from months/years of overgrowth. Now, if you
knock it down to normal levels (90% to 100% total clearance) then it
is MUCH easier to maintain remission because they need a long time
to take hold, build their environment again and replicate. So, it
is a matter of percent clearance of the number of yeast in the pores
and not the superficial clearance of the disorder. That is why the
Azoline holds great promise for long term remission or very easy
maintenance. I hope that made some sense.
Regards,
Geoffrey