Archive for December, 2004

Sporanox

Friday, December 31st, 2004

On May 9, 2001. The Food and Drug Administration (FDA) issued a
Public Health Advisory to announce significant safety-related updates
to the labeling of Sporanox products and Lamisil tablets. Sporanox
and Lamisil are used to treat nail (onychomycosis), skin and other
systemic fungal infections.

Potential Heart Damage

The FDA believes there is real risk of developing congestive heart
failure (CHF) associated with the use of Sporanox. Both Sporanox and
Lamisil have been associated with serious liver problems resulting in
liver failure, transplantation and even death.

Results of recent studies of Sporanox showed that the drug can weaken
the force of the heart muscle’s contractions. This condition,
(more…)

Even more on itraconazole

Thursday, December 30th, 2004

Key issues Itraconazole is an established, broad-spectrum antifungal
agent with documented in vivo activity against dermatophytes, yeasts
and moulds and an excellent safety profile. Itraconazole tends to
accumulate in keratinous tissues and organs often involved in fungal
infections, such as the lungs. Full exploitation of this
pharmacokinetic profile has led to the development of pulse treatment
regimens that allow similar efficacy with lower overall drug exposure
as well as a reduction in treatment costs. Due to its anti-
inflammatory properties, itraconazole is emerging as the treatment of
choice in inflammatory skin conditions that otherwise have a high
relapse rate, such as seborrheic dermatitis and atopic dermatitis of
the face. Development of new oral liquid and intravenous formulations
has extended the application of itraconazole to systemic fungal
infections, both as standard treatment and as prophylactic and
empiric treatment in immunocompromised hosts.

More on Itraconazole (Sporanox)

Thursday, December 30th, 2004

Drug effective against underlying fungal infection
September 15, 2002 By: Paula Moyer Dermatology Times

Patient at baseline (left) and one week itraconazole posttreatment.
New Orleans - Disorders that seemingly have no mycotic component
could respond
to a course of itraconazole (Sporanox), according to Ruggero Caputo,
M.D. In
fact, for certain patients, it may have a role in the treatment of
inflammatory
diseases such seborrheic dermatitis, atopic dermatitis, and rosacea,
as well as
palmo plantar amicrobic pustulosis.

"The oral administration of itraconazole may be useful in different
(more…)

Itraconazole treatment - January 2004

Wednesday, December 29th, 2004

Itraconazole in the treatment of seborrheic dermatitis: a new
treatment modality.

Baysal V, Yildirim M, Ozcanli C, Ceyhan AM.

BACKGROUND: Due to the high rate of recurrence, seborrheic dermatitis
(SD) represents a therapeutic problem. AIM: To evaluate the role of
oral itraconazole in the treatment of SD. PATIENTS AND METHODS:
Thirty-two patients with SD were enrolled in the study. All topical
and oral treatments were stopped. The patients applied 1%
hydrocortisone cream twice daily for 1 month. In addition, they took
itraconazole, 200 mg/day, during the first week of the first month
and then hydrocortisone cream was stopped and itraconazole (200
mg/day) was given on the first 2 days of the following 11 months. The
patients were followed for 2 months without medicine. The severity
(more…)

DRL Updates?

Wednesday, December 29th, 2004

Hi,
I’m considering trying DRL again. I used it for a while last summer,
but my skin was so oily that I think it may have interfered with the
lotion. I’ve been taking B5 for the past 9 months with good results -
about a 75% reduction in oil. My face is still red, though. So, I’m
wondering how the different versions of DRL are working out for
people, especially if you have oily skin. I’m considering trying the
oily skin version or maybe the extra strength version. Any ideas on
this?
As always, thanks for your comments.
Tim

100 % TEA TREE OIL

Tuesday, December 28th, 2004

I have had what has been diagnosed as seb derm on my scalp for YEARS.
I have tried just about EVERY shampoo and other remedy but NOTHING
gives me the relief of 100% tea tree oil. It’s really a Godsend! Has
anyone eles gotten relief from this also?

Allergic to Coffee

Saturday, December 25th, 2004

Good Morning Group

Yesterday evening at the internal medical office I justt found out that I am
allergic to coffee, not caffene but coffee. She told me to stop drinking it
immediately. amongst other things, the doctor told me that coffee was
causing stress on my internal organs such as liver, kidneys, gal bladder and
all the other mess inside. Just one of the pointers from my last interview
with the doctor.

interesting though - i began drinking coffee out of college when i began to
work as a professional about 4 years ago. I only would drink it because it
was in the break room and everyone was doing it, so i decided to aswell. I
was never really a coffee drinker. Around the same time 4 years ago, signs
of seb derm became apparent. I also remember that in my trip to australia i
was seb derm free for 3 weeks while i was over there. I also remember not
(more…)

Cosmetic ingredients and irritation ?

Wednesday, December 22nd, 2004

Hi folks,

I just found out the hard way that folks with seb derm may need to be
careful about what we put on our skin. I ran out of nizoral cream, so
I tried some OTC miconazol cream that I had. Yikes…I must have had
a bad reaction to some of the ingredients because my face was red and
irritated the next morning. Now, I remember my dermatologist telling
me to be careful with skin care since even water can act as an
irritant to sensitive skin. I guess he wasn’t kidding. Here’s some
links to cosmetic ingredients that might cause problems:

Take care… Michael

www.zerozits.com/Articles/article6.htm
www.beautymagonline.com/pages/sensitisers.htm
(more…)

New to Subderm

Tuesday, December 21st, 2004

Hi All,

Just recently was "officially" diagnosed with SD. I have it on the
sides of my nose but no where else. It started almost a year ago
after my second child. I became pregnant very soon after my second
and my face was just awful. I finally got to see a dermatologist and
quite frankly left there thinking that I wasted my time. The doctor
prescribed dermatop and loprox shampoo. He told me to wash my hair
with loprox and let the soap drip onto my face in the shower. It
started working very quickly and I saw some improvement with the
dermatop. My face is better than it’s been in over a year, but I
still have big red patches on the sides of my nose. Has anyone ever
had this problem? Without makeup, I don’t even want to leave the
house some days. The dermatop ointment that he prescribed helped to
soften the skin and relieve any flaking I was having, but it affected
(more…)

Cutanix DRL - progress

Monday, December 20th, 2004

I received the Cutanix for sensitive skin about a month ago. I was
dealing with a bad breakout of SD over Christmas. I had been using
OTC Hydrocortisone and had gotten my forehead under control. My Chin
and around my nose was still flaking somewhat.

So I started using the Cutanix on my forehead and stopped using any
hydrocortisone in that area. The cutanix has left my skin very
smooth and very hydrated. (the best is has felt in over 2 years) The
first week I broke out with little bumps, but decided to ride it
out. THe bumps disappeared and I have not had one flake on my
forehead.

Around my chin and nose is a different story. Over the past month
those areas had been red and inflamed and if I try to put the cutanix
on it, it was irratating and left a burning sensation. But as of
(more…)